mafft-1.6.2run 2 x Intel Xeon E5-2620 v2 testing with a ASUS Z9PE-D8 WS (5503 BIOS) and ASPEED on CentOS Stream 9 via the Phoronix Test Suite. debug: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 256GB Samsung SSD 850 + 2000GB Western Digital WD20EARX-00P, Graphics: ASPEED, Audio: Realtek ALC898, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-467.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.4.1 20231218 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 NoGVNO2: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 256GB Samsung SSD 850 + 2000GB Western Digital WD20EARX-00P, Graphics: ASPEED, Audio: Realtek ALC898, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-467.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.4.1 20231218 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 NoGVNO3: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 256GB Samsung SSD 850 + 2000GB Western Digital WD20EARX-00P, Graphics: ASPEED, Audio: Realtek ALC898, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-467.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.4.1 20231218 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 OptNoSimplO2: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 2000GB Western Digital WD20EARX-00P + 256GB Samsung SSD 850, Graphics: ASPEED, Audio: Realtek ALC898, Monitor: ASUS VW190, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-474.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.4.1 20231218 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 OptNoSimplO3: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 2000GB Western Digital WD20EARX-00P + 256GB Samsung SSD 850, Graphics: ASPEED, Audio: Realtek ALC898, Monitor: ASUS VW190, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-474.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.4.1 20231218 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 OptSimplO2: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 2000GB Western Digital WD20EARX-00P + 256GB Samsung SSD 850, Graphics: ASPEED, Audio: Realtek ALC898, Monitor: ASUS VW190, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-474.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.4.1 20231218 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 OptSimplO3: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 2000GB Western Digital WD20EARX-00P + 256GB Samsung SSD 850, Graphics: ASPEED, Audio: Realtek ALC898, Monitor: ASUS VW190, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-474.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.4.1 20231218 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 OptRedO2: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 2000GB Western Digital WD20EARX-00P + 256GB Samsung SSD 850, Graphics: ASPEED, Audio: Realtek ALC898, Monitor: ASUS VW190, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-474.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.4.1 20231218 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 OptRedO3: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 2000GB Western Digital WD20EARX-00P + 256GB Samsung SSD 850, Graphics: ASPEED, Audio: Realtek ALC898, Monitor: ASUS VW190, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-474.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.4.1 20231218 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 2 x Intel Xeon E5-2620 v2: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 2000GB Western Digital WD20EARX-00P + 256GB Samsung SSD 850, Graphics: ASPEED, Audio: Realtek ALC898, Monitor: ASUS VW190, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-480.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.4.1 20231218 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 OptPREO2: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 2000GB Western Digital WD20EARX-00P + 256GB Samsung SSD 850, Graphics: ASPEED, Audio: Realtek ALC898, Monitor: ASUS VW190, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-480.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.4.1 20231218 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 GVNO2: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 2000GB Western Digital WD20EARX-00P + 256GB Samsung SSD 850, Graphics: ASPEED, Audio: Realtek ALC898, Monitor: ASUS VW190, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-480.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.4.1 20231218 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 NewGVNO2: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 2000GB Western Digital WD20EARX-00P + 256GB Samsung SSD 850, Graphics: ASPEED, Audio: Realtek ALC898, Monitor: ASUS VW190, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-480.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.4.1 20231218 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 OptPREO3: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 2000GB Western Digital WD20EARX-00P + 256GB Samsung SSD 850, Graphics: ASPEED, Audio: Realtek ALC898, Monitor: ASUS VW190, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-480.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.4.1 20231218 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 NewGVNO333: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 256GB Samsung SSD 850 + 2000GB Western Digital WD20EARX-00P, Graphics: ASPEED, Audio: Realtek ALC898, Monitor: ASUS VW190, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-496.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.5.0 20240719 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 GVNO3: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 256GB Samsung SSD 850 + 2000GB Western Digital WD20EARX-00P, Graphics: ASPEED, Audio: Realtek ALC898, Monitor: ASUS VW190, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-496.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.5.0 20240719 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 PessimisticO3: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 256GB Samsung SSD 850 + 2000GB Western Digital WD20EARX-00P, Graphics: ASPEED, Audio: Realtek ALC898, Monitor: ASUS VW190, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-503.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.5.0 20240719 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 PessimisticO2: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 256GB Samsung SSD 850 + 2000GB Western Digital WD20EARX-00P, Graphics: ASPEED, Audio: Realtek ALC898, Monitor: ASUS VW190, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-503.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.5.0 20240719 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 PessimisticNewGVNO2: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 256GB Samsung SSD 850 + 2000GB Western Digital WD20EARX-00P, Graphics: ASPEED, Audio: Realtek ALC898, Monitor: ASUS VW190, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-503.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.5.0 20240719 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 PessimisticNewGVNO3: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 256GB Samsung SSD 850 + 2000GB Western Digital WD20EARX-00P, Graphics: ASPEED, Audio: Realtek ALC898, Monitor: ASUS VW190, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-503.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.5.0 20240719 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 NewGVNO2-debug: Processor: 2 x Intel Xeon E5-2620 v2 @ 2.60GHz (12 Cores / 24 Threads), Motherboard: ASUS Z9PE-D8 WS (5503 BIOS), Chipset: Intel Xeon E7 v2/Xeon, Memory: 32GB, Disk: 256GB Samsung SSD 850 + 2000GB Western Digital WD20EARX-00P, Graphics: ASPEED, Audio: Realtek ALC898, Monitor: ASUS VW190, Network: 2 x Intel 82574L OS: CentOS Stream 9, Kernel: 5.14.0-514.el9.x86_64 (x86_64), Display Server: X Server, Display Driver: NVIDIA, Compiler: GCC 11.5.0 20240719 + PGI Compiler 16.10-0 + LLVM 3.1 + CUDA 11.2, File-System: ext4, Screen Resolution: 1024x768 Timed MAFFT Alignment 7.471 Seconds < Lower Is Better Timed MAFFT Alignment 7.471 Multiple Sequence Alignment - LSU RNA Seconds < Lower Is Better OptNoSimplO2 .............. 38.72 |=========================================== OptNoSimplO3 .............. 38.92 |============================================ OptSimplO2 ................ 39.03 |============================================ OptSimplO3 ................ 38.88 |=========================================== OptRedO3 .................. 38.89 |=========================================== 2 x Intel Xeon E5-2620 v2 . 38.91 |============================================ 2 x Intel Xeon E5-2620 v2 . 38.14 |=========================================== debug ..................... 22.75 |========================= NoGVNO2 ................... 38.93 |============================================ NoGVNO3 ................... 39.20 |============================================ OptNoSimplO2 .............. 38.93 |============================================ OptNoSimplO3 .............. 39.09 |============================================ OptSimplO2 ................ 38.94 |============================================ OptSimplO3 ................ 38.66 |=========================================== OptRedO2 .................. 38.79 |=========================================== OptRedO3 .................. 39.19 |============================================ 2 x Intel Xeon E5-2620 v2 . 38.84 |=========================================== OptPREO2 .................. 39.12 |============================================ GVNO2 ..................... 38.77 |=========================================== NewGVNO2 .................. 38.84 |=========================================== OptPREO3 .................. 38.78 |=========================================== NewGVNO333 ................ 38.50 |=========================================== GVNO3 ..................... 38.67 |=========================================== PessimisticO3 ............. 39.35 |============================================ PessimisticO2 ............. 39.27 |============================================ PessimisticNewGVNO2 ....... 39.19 |============================================ PessimisticNewGVNO3 ....... 39.10 |============================================ NewGVNO2-debug ............ 38.22 |=========================================== Timed MAFFT Alignment 7.471 Test Install Size Bytes < Lower Is Better 2 x Intel Xeon E5-2620 v2 . 15412 |============================================ 2 x Intel Xeon E5-2620 v2 . 15416 |============================================ NewGVNO2-debug ............ 15412 |============================================